| Position |
Columnname |
Description |
| 1 |
Hugo_Symbol |
HUGO symbol for the gene (HUGO symbols are always in all caps). "Unknown" is used for regions that do not correspond to a gene |
| 2 |
Entrez_Gene_Id |
Entrez gene ID (an integer). "0" is used for regions that do not correspond to a gene region or Ensembl ID |
| 3 |
Center |
One or more genome sequencing center reporting the variant |
| 4 |
NCBI_Build |
The reference genome used for the alignment (GRCh38) |
| 5 |
Chromosome |
The affected chromosome (chr1) |
| 6 |
Start_Position |
Lowest numeric position of the reported variant on the genomic reference sequence. Mutation start coordinate |
| 7 |
End_Position |
Highest numeric genomic position of the reported variant on the genomic reference sequence. Mutation end coordinate |
| 8 |
Strand |
Genomic strand of the reported allele. Currently, all variants will report the positive strand: '+' |
| 9 |
Variant_Classification |
Translational effect of variant allele |
| 10 |
Variant_Type |
Type of mutation. TNP (tri-nucleotide polymorphism) is analogous to DNP (di-nucleotide polymorphism) but for three consecutive nucleotides. ONP (oligo-nucleotide polymorphism) is analogous to TNP but for consecutive runs of four or more (SNP, DNP, TNP, ONP, INS, DEL, or Consolidated) |
| 11 |
Reference_Allele |
The plus strand reference allele at this position. Includes the deleted sequence for a deletion or "-" for an insertion |
| 12 |
Tumor_Seq_Allele1 |
Primary data genotype for tumor sequencing (discovery) allele 1. A "-" symbol for a deletion represents a variant. A "-" symbol for an insertion represents wild-type allele. Novel inserted sequence for insertion does not include flanking reference bases |
| 13 |
Tumor_Seq_Allele2 |
Tumor sequencing (discovery) allele 2 |
| 14 |
dbSNP_RS |
The rs-IDs from the dbSNP database, "novel" if not found in any database used, or null if there is no dbSNP record, but it is found in other databases |
| 15 |
dbSNP_Val_Status |
The dbSNP validation status is reported as a semicolon-separated list of statuses. The union of all rs-IDs is taken when there are multiple |
| 16 |
Tumor_Sample_Barcode |
Aliquot barcode for the tumor sample |